Preheat oven to 325 degrees and grease a 9x13 baking dish.
Combine cake mix, melted butter, peanut butter, and egg in a large bowl using a mixer or spoon. Press the cake mixture into prepared baking dish reserving 1 1/4 cup of the mixture to crumble on top.
In a small pot, melt chocolate chips, sweetened condensed milk, and butter. Remove from heat and stir in the vanilla.
Spread chocolate mixture over the mixture pressed in the pan and then crumble the 1 1/4 cups of reserved cake mixture on top evenly.
Bake for 20-25 minutes. Cool completely before cutting into bars.